Woof Woof – Bone marrow cells are coming
Bone marrow contains cells that can travel to multiple organ sites and differentiate into specific tissue cells. Bone marrow-derived stem cells have also been associated with the pathogenesis of endometriosis. These cells can affect epithelial and stromal cell regeneration both…
Key Points Lay SummaryCXCR4 or CXCR7 antagonists as novel therapies for endometriosis
Endometriosis is a common, estrogen-dependent chronic inflammatory disorder. It affects approximately 5-10% of reproductive-aged women and 20-50% of infertile women. Endometriosis also has a significant social and psychological impact on the lives of women. Despite such a significant burden, there…
Key Points Lay SummaryTherapeutic strategies involving uterine stem cells in reproductive medicine
Stem cells are undifferentiated cells that often serve to regenerate tissue in states of injury or apoptosis. The endometrium has progenitor cells that replace tissue lost after each menstrual cycle. It has been postulated that excessive stem cell recruitment to…
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